SEVERE HEART PUMPING DYSFUNCTION/ HEART FAILURE

Heart failure is a disorder in which the heart is unable to keep up the demands of the body, leading to reduced blood flow, back up of blood in the veins and lungs or other changes that may further weaken or stiffen the heart.

Heart failure does not means that the heart has stopped it means heart cannot keep up the work required to pump adequate blood to all parts of the body.

The function of the heart is to pump. The right side of the heart pumps blood from the veins in to the lungs. The left side of the heart pumps blood from the lungs out through the arteries to the rest of the body.

Blood goes out of the heart when the heart muscle contracts (called systole) and comes into the heart when the heart muscle relaxes (called diastole).

Heart failure develops when the contracting or the relaxing action of the heart is inadequate, typically because the heart muscle is weak, stiff, or both. Heart failure may be described as left sided heart failure or right sided heart failure.

The main pumping chambers of the heart (the ventricles)

  1. Left side heart failure: Fluid may backup in the lungs, causing shortness of breath.
  2. Right side heart failure: Fluid may back up in to the abdomen, legs and feet, causing swelling.
  3. Systolic heart failure: The left ventricle cannot contract vigorously, indicating pumping problem.
  4. Heart failure with preserved ejection fraction: The left ventricle cannot relax or full fully indicating a filling problem.

Types of heart failure

The heart failure is classified by the ejection fraction (EF), which is the percentage of blood pumped out by the heart with each beat. A normal left ventricular ejects about 55 to 60% of blood.

Ventricular assist device
Heart failure with reduced ejection fraction (systolic heart failure)

The heart contracts less forcefully and pumps out a lower percentage of the blood that is returned to it. As a result, more blood remains in the heart. Blood then accumulates in the lungs, veins, or both.

Heart failure with preserved ejection fraction (diastolic heart failure)

The heart is stiff and does not relax normally after contracting, which impairs its ability to fill with blood. The stiff heart compensates for its poor filling by pumping out an even higher proportion of the blood than it normally does. Eventually, as in systolic heart failure, the blood returning to the heart accumulates in the lungs or veins.

Heart failure with mid range ejection fraction

It is a newer concept that includes people whose ejection fraction is somewhere between preserved and reduced ejection fraction.

New York heart association classified a scale on heat failure

  • Class I heart failure: There are no heart failure symptoms.
  • Class II heart failure: Everyday activities can be done without difficulty but exertion causes shortness of breath or fatigue.
  • Class III heart failure: It is difficult to complete everyday activities.
  • Class IV heart failure: Shortness of breath occurs even at rest. This category includes the most severe heart failure.
heart failure

Causes

High blood pressure.
  • Coronary artery disease: The blood flowing to your heart is blocked or less than normal
  • Cardiomyopathy: when heart muscle is damaged the heart cannot pump blood to the normal.
  • Heart valve problems: when heart valves doesn’t open or close the way they function or they become leak in such cases the heart has to pump harder to get blood through your body.
  • Congenital heart defect
  • Abnormal heart rhythms (arrhythmias)
  • Other diseases: diabetes, HIV, over active or under active thyroid or buildup iron or protein
  • Alcohol use
  • Sleep apnea
  • Smoking or using tobacco
  • Obesity
  • Viruses

Sign and Symptoms

Shortness of breath
  • Tiredness
  • Weakness
  • Swelling in feet, ankles, legs, or abdomen
  • Cough or wheezing
  • Dizziness
  • Confusion
  • Nausea
  • Lack of appetite

Diagnosis

Blood tests
  • Electrocardiogram (EKG)
  • Chest x-ray
  • Echocardiogram (ECG)
  • Exercise test
  • Heart catheterization
  • CT scan
  • MRI
  • Coronary angiogram
  • Stress test

Prevention

Preventing heart failure involves treating the disorders that causing heart failure
  • High blood pressure
  • Obesity
  • Obstructive sleep apnea
  • Blockage of the coronary artery
  • Heart valve disorders
  • Abnormal heart rhythms
  • Alcoholism
  • Anemia
  • Thyroid disorders

Complications

Kidney damage or failure
  • Liver damage
Heart pacemaker

Drugs for heart failure

  • Drugs to relive symptoms: Diuretics, Nitrates, Digoxin
  • Drugs the helps to improve survival: Angiotensin converting enzyme inhibitors, Beta blockers, Aldosteron antagonist, Angiotensin II receptor blockers, Angiotensin receptor inhibitors, Sodium glucose co-transporter 2 inhibitors, sinus node inhibitors.

The type of drug used depends on the type of heart failure. In systolic heart failure all the drug classes are helpful. In diastolic heart failure only ACE inhibitors, ARBs, Aldosterone antagonists and beta-blockers are typically used.

Heart bypass surgery

The following surgeries and devises may be required for some patients with heart failure

1. Heart bypass surgery

Heart bypass surgery creates a new route, called a bypass, for blood and oxygen to go around a blockage to reach your heart. The patient will be given general anesthesia. Once the patient is unconscious the heart surgeon will make an 8 to 10-inch (20.5 to 25.5 cm) surgical cut in the middle of your chest. Your breastbone will be separated to create an opening. This allows your surgeon to see your heart and aorta, the main blood vessel leading from the heart to the rest of your body.

Most people who have coronary bypass surgery are connected to a heart-lung bypass machine, or bypass pump. Your heart is stopped while you are connected to this machine. This machine does the work of your heart and lungs while your heart is stopped for the surgery. The machine adds oxygen to your blood, moves blood through your body, and removes carbon dioxide.

Risks
  • Infection
  • Heart attack
  • Stroke
  • Kidney failure
  • Lung failure
  • Bleeding
Prognosis
  • Eating a heart-healthy diet
  • Getting regular exercise

Treating high blood pressure and diabetes

2. Heart valve surgery

Heart valve surgery is used to repair or replace diseased heart valves. Blood that flows between different chambers of your heart must flow through a heart valve. Blood that flows out of your heart into large arteries must also flow through a heart valve.

There are 4 valves in your heart:

  • Aortic valve
  • Mitral valve
  • Tricuspid valve
  • Pulmonic valve

Aortic valve and mitral valve are the most common valve to be repaired. Rarely tricuspic and pulmonic valve replaced or repaired.

Before surgery you will receive general anesthesia.

In open heart surgery, the surgeon makes a large surgical cut in your breastbone to reach the heart and aorta. You are connected to a heart-lung bypass machine if your heart is stopped while connecting to this machine. This machine does the work of your heart, providing oxygen and removing carbon dioxide.

Minimally invasive valve surgery is done through much smaller cuts than open surgery, or through a catheter inserted through the skin. Several different techniques are used:

  1. Percutaneous surgery
  2. Robot surgery
If surgeon can repair mitral valve
  • Ring annuloplasty:  Repairs the ring-like part around the valve by sewing a ring of plastic, cloth, or tissue around the valve.
  • Valve repair: The surgeon trims, shapes, or rebuilds one or more of the leaflets of the valve. The leaflets are flaps that open and close the valve. Valve repair is best for the mitral and tricuspid valves. The aortic valve is usually not repaired
If your valve is too damaged then the valve replacement to be done

Types of valves

  • Mechanical : Manmade materials such as metals or ceramics
  • Biological: Made of human or animal tissues this last 10-15 years
Heart valve surgery
Heart pacemaker

3. Heart pacemaker

A pacemaker is a small, battery-operated device. This device senses when your heart is beating irregular or too slowly

  • Pacemakers weigh as little as 1 ounce (28 grams). Most pacemakers have 2 parts.
  • The generator contains the battery and the information to control the heartbeat.
  • The leads are wires that connect the heart to the generator and carry the electrical messages to the heart.
  • A pacemaker is implanted under the skin this procedure takes 1 hour in most of the cases
  • You will be awake during the procedure
  • A small incision is made on the left side of the chest below your collarbone. A pacemaker generator is then placed under the skin at this location
  • Using live x-ray to see the area the doctors puts the leads through the cuts in to the veins and then in to heart. This leads are connected to the generator. There are two types
    • Transcutaneous pacemaker
    • Transvenous pacemaker
Why the procedure is performed

When your heart beats too slowly, your body and brain may not get enough oxygen. Symptoms may be

  • Light headedness
  • Tiredness
  • Fainting spells
  • Shortness of breath
Risks
  • Abnormal heart rhythms
  • Bleeding
  • Punctured lung
  • Infection
  • Puncture of the heart, which can lead you breathing around the heart
Prognosis

Pacemakers can help keep your heart rhythm and heart rate at a safe level for you. The pacemaker battery lasts about 6 to 15 years. Your provider will check the battery regularly and replace it when necessary.

4. Implantable Cardioverter-defibrillator

ICD is a device that detects any life threatening, rapid heat beat. If an arrhythmia occurs ICD quickly sends an electrical shock to the heart. The shock changes the rhythm back to normal. This is called defibrillation.

The ICD is made of 3 parts

  • The pulse generator contains battery and electrical circuit that reads the electrical activity of your heart
  • Your ICD has 1, 2, 3 electrodes. Most ICD has built in pacemaker.
  • There is a special kind of ICD called a subcutaneous ICD. This device has a lead that is placed in the tissue to the left of the breastbone rather than in the heart. This type of ICD cannot also be a pacemaker.
  • The surgeon will place the electrode into a vein, then into your heart. This is done using a special x-ray to see inside your chest. Then the surgeon will connect the electrodes to the pulse generator and pacemaker. This procedure takes 2 to 3 hours.
Why the procedure is performed
  • Episodes of abnormal heart rhythms
  • Congenital heart problems or genetic health condition
Risks
  • Blood clots in the lungs that mat travel to the lungs
  • Breathing problems
  • Heart attack or stroke
  • Allergic reaction
  • Infection
Prognosis

Your ICD will constantly monitor your heartbeats to make sure they are steady. It will deliver a shock to the heart when it senses a life-threatening rhythm. Most of these devices can also work as a pacemaker.

End stage heart failure

Severe heart failure occurs when treatments no longer work. Certain treatments may be used when a person is waiting for (or instead of) a heart transplant.

  1. Intra aortic balloon pump
  2. Ventricular assist device
  3. Total artificial heart
Implantable Cardioverter-defibrillator
Ventricular assist device

Ventricular assist device

Ventricular assist devices (VADs) help your heart pump blood from one of the main pumping chambers to the rest of your body or to the other side of the heart. These pumps are implanted in your body. In most cases they are connected to machinery outside your body.

A ventricular assist device has 3 parts:

 Pump: The pump weighs 1 to 2 pounds (0.5 to 1 kilogram). It is placed inside or outside of your belly.

An electronic controller: The controller is like a small computer that controls how the pump works.

Batteries or another power source: The batteries are carried outside your body. They are connected to the pump with a cable that goes into your belly.

During surgery
  • The heart surgeon opens the middle of your chest with a surgical cut and then separates your breastbone. This allows access to your heart.
  • Depending on the pump used, the surgeon will make space for the pump under your skin and tissue in the upper part of your belly wall.
  • The surgeon will then place the pump in this space.
  • A tube will connect the pump to your heart. Another tube will connect the pump to your aorta or one of your other major arteries. Another tube will be passed through your skin to connect the pump to the controller and batteries.
  • Surgery most often lasts 4 to 6 hours.
  • There are other types of VADs (called percutaneous ventricular assist devices) which can be placed with less invasive techniques to help the left or right ventricle. However, these typically cannot provide as much flow (support) as the surgically implanted ones.
Why the procedure is performed

You may need a VAD if you have severe heart failure that cannot be controlled with medicine, pacing devices, or other treatments. You may get this device while you are on a waiting list for a heart transplant. Some people who get a VAD are very ill and may already be on a heart-lung support machine.

Risks
  • Blood clots in the legs that may travel to the lungs
  • Blood clots that form in the device and can travel to other parts of the body
  • Breathing problems
  • Heart attack or stroke
  • Allergic reactions
  • Infections
  • Bleeding
Prognosis

A VAD may help people who have heart failure live longer. It may also help improve patients’ quality of life.

Overall prognosis of heart failure

Heart failure can get suddenly worse due to

  • Ischemia (lack of blood flow to the heart muscle)
  • Eating high-salt foods
  • Heart attack
  • Infections or other illnesses
  • Not taking medicines correctly
  • Abnormal heart rhythms
When to contact medical professional
  • Increased cough or phlegm
  • Sudden weight gain or swelling
  • Weakness
  • Go to emergency room when you have symptoms like
  • You faint
  • If you have fast and irregular heartbeat
Alternative names

CHF; congestive heart failure; left sided heart failure; right sided heart failure; cardiomyopathy; heart failure