LMCA

LEFT MAIN CORONARY
ARTERY LESIONS

Left main coronary artery (LMCA) despite its short length is the most challenging area for both cardiovascular surgeons and interventional cardiologists.
Significant LMCA disease is defined as a greater than 50% angiographic narrowing of the vessel.
The LMCA is responsible for supplying about 75% of the LV cardiac mass in patients with right dominant type and 100% in the case of left dominant type.
Severe LMCA disease = significantly reduced blood flow to a large portion of the myocardium which will put the patient at high risk for LV dysfunction and arrhythmias.

Diagnosis of LMCA disease:

  • Most patients with LMCA disease are symptomatic.
  • Usually made by coronary angiography.

LMCA Treatments

There are three options for treating LMCA disease
  • Medical therapy
  • PCI
  • CABG

Preventive
Therapies

LMCA patients should receive preventive therapies – reduce risk of subsequent cardiovascular events
  • Smoking cessation
  • Exercise
  • Lower lipid levels
  • Management of diabetes mellitus
  • Achieve target blood pressure goals

Treatment of LMCA

Surgical treatment of LMCA disease
  • CABG was regarded as the standard of care
  • PCI has emerged as a possible alternative method
  • Patient characteristics and lesion location are important factors for the determination of treatment of choice. Operator’s experience and technical considerations also play a major role.